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Genes

Several genes have been implicated in Alzheimer's, but the big one is the e4 allele of the ApoE gene (on chromosome 19). This variant is found in about a quarter of the population.

Having it doesn't mean you are foreordained to develop Alzheimer's, but it certainly increases the risk substantially. The risk goes up considerably more if both of your genes are the e4 variant (remember you inherit two: one from each parent).

The evidence that diet, physical exercise, and mental stimulation all help prevent age-related cognitive decline and reduce the risk of mild cognitive impairment and Alzheimer’s, is now very convincing.

Studies of mice and (rather intriguingly) beagles, have provided evidence that ‘enriched’ environments — ones that provide opportunities for regular exercise and mental stimulation — reduce or prevent age-related cognitive decline, and reduce the risk of Alzheimer’s.

As I said in my discussion of different scripts, the Hellenic languages use the Greek alphabet. Here it is. I’m afraid the table is a little complicated, because (a) each letter has a name, which it’s useful to know, and (b) there are some differences in pronunciation between Ancient Greek (which is still a language that people want to learn today), and Modern Greek.

A fascinating article recently appeared in the Guardian, about a woman who found a way to overcome a very particular type of learning disability and has apparently helped a great many children since.

I recently reported on a finding that older adults whose life-space narrowed to their immediate home were significantly more likely to have a faster rate of global cognitive decline or develop mild cognitive impairment or Alzheimer’s.

Subliminal learning achieved notoriety back in 1957, when James Vicary claimed moviegoers could be induced to buy popcorn and Coca-Cola through the use of messages that flashed on the screen too quickly to be seen. The claim was later shown to be false, but though the idea that people can be brainwashed by the use of such techniques has been disproven (there was quite a bit of hysteria about the notion at the time), that doesn’t mean the idea of subliminal learning is crazy.

When we are presented with new information, we try and connect it to information we already hold. This is automatic. Sometimes the information fits in easily; other times the fit is more difficult — perhaps because some of our old information is wrong, or perhaps because we lack some of the knowledge we need to fit them together.

Types of reading disability

A longitudinal study that used imaging to compare brain activation patterns has identified two types of reading disability:

Transfer refers to the ability to extend (transfer) learning from one situation to another. For example, knowing how to play the piano doesn’t (I assume) help you play the tuba, but presumably is a great help if you decide to take up the harpsichord or organ. Similarly, I’ve found my knowledge of Latin and French a great help in learning Spanish, but no help at all in learning Japanese.

Impaired vision is common in old age and even more so in Alzheimer’s disease, and this results not only from damage in the association areas of the brain but also from problems in lower-level areas. A major factor in whether visual impairment impacts everyday function is contrast sensitivity.