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Brain tissue is divided into two types: gray matter and white matter. These names derive very simply from their appearance to the naked eye. Gray matter is made up of the cell bodies of nerve cells. White matter is made up of the long filaments that extend from the cell bodies - the "telephone wires" of the neuronal network, transmitting the electrical signals that carry the messages between neurons.

The volume of gray matter tissue - a measure you will see cited in various reports - is a measure of the density of brain cells in a particular region.

Genes

Several genes have been implicated in Alzheimer's, but the big one is the e4 allele of the ApoE gene (on chromosome 19). This variant is found in about a quarter of the population.

Having it doesn't mean you are foreordained to develop Alzheimer's, but it certainly increases the risk substantially. The risk goes up considerably more if both of your genes are the e4 variant (remember you inherit two: one from each parent).

Transfer refers to the ability to extend (transfer) learning from one situation to another. For example, knowing how to play the piano doesn’t (I assume) help you play the tuba, but presumably is a great help if you decide to take up the harpsichord or organ. Similarly, I’ve found my knowledge of Latin and French a great help in learning Spanish, but no help at all in learning Japanese.

Humans have a long tradition of holding genes responsible for individual differences in behavior (of course, we called it "blood", then, or "family"). In the 20th century, a counter-belief arose: that it was all down to environment, to upbringing. In more recent decades, we have become increasingly aware of how tightly and complexly genes and environment are entwined.

Context is absolutely critical to successful communication. Think of the common experience of being a stranger at a family gathering or a meeting of close friends. Even familiar words and phrases may take on a different or additional meaning, among people who have a shared history. Many jokes and comments will be completely unintelligible, though you all speak the same language.

Nowadays every school has to have computers. I don't refer to legal requirementbut to perception. Schools are judged on how many computers they have. It would be more to the point if they were judged on their computer-savvy.

In a 1987 experiment (1), readers were presented with a text that included one or other of these sentences:

or

Both texts went on to say:

Elaborative interrogation is a strategy to help you remember meaningful information. The idea behind the strategy is that relevant prior knowledge is not always readily activated when you are trying to learn new information, and sometimes help is needed to make the right connections. The strategy requires you to go beyond the information given to you and to construct reasons for the relationships between bits of information.

The Seattle Longitudinal Study of Adult Intelligence has followed a group of more than 5000 people for well over four decades. The program began in 1956 and participants have been tested across a whole gamut of mental and physical abilities at seven year intervals since that date.

The study has found:

Song is a wonderful way to remember information, although some songs are better than others. Songs that help you remember need to have simple tunes, with a lot of repetition -- although a more complex tune can be used if it is very familiar. Most importantly, the words should be closely tied to the tune, so that it provides information about the text, such as line and syllable length. You can read more about this in my article on Music as a mnemonic aid, but here I simply want to mention a few specific songs designed for teaching facts.