Several genes have been implicated in Alzheimer's, but the big one is the e4 allele of the ApoE gene (on chromosome 19). This variant is found in about a quarter of the population.
Having it doesn't mean you are foreordained to develop Alzheimer's, but it certainly increases the risk substantially. The risk goes up considerably more if both of your genes are the e4 variant (remember you inherit two: one from each parent).
The conventional view of brain development has been that most of this takes place in utero and in the first three years, with the further development continuing until the brain is fully mature at around 10-12 years of age. The turbulence of adolescent behavior has been deemed to be mostly caused by hormonal changes. Piaget, who identified four stages of cognitive development, assessed that his highest stage — that of formal, abstract reasoning — occurred around 13-14 years (although not everyone reaches this level, which requires appropriate education).
Having trouble sleeping is perfectly normal, especially as we age. It’s estimated that half of those older than 55 have trouble getting to sleep or staying asleep.
Let’s start with the easiest situation: you’re not getting enough sleep because you wilfully go to bed too late to achieve your needs.
I recently read an interesting article in the Smithsonian about procrastination and why it’s good for you. Frank Partnoy, author of a new book on the subject, pointed out that procrastination only began to be regarded as a bad thing by the Puritans — earlier (among the Greeks and Romans, for example), it was regarded more as a sign of wisdom.
Difficulty in remembering people’s names is one of the most common memory tasks that people wish to be better at. And the reason for this is not that their memory is poor, but because it is so embarrassing when their memory lets them down.
This isn’t just an issue at a personal level. It’s a particular issue for anyone who has to deal with a lot of people, many of whom they will see at infrequent intervals. Nothing makes a person — a client, a customer, a student — feel more valued than being remembered.
A lot of theories have been thrown up over the years as to what we need sleep for (to keep us wandering out of our caves and being eaten by sabertooth tigers, is one of the more entertaining possibilities), but noone has yet been able to point to a specific function of the sleep state that would explain why we have it and why we need so much of it.
Michael Gove is reported as saying that ‘Learning facts by rote should be a central part of the school experience’, a philosophy which apparently underpins his shakeup of school exams. Arguing that "memorisation is a necessary precondition of understanding", he believes that exams that require students to memorize quantities of material ‘promote motivation, solidify knowledge, and guarantee standards’.
On my walk today, I listened to a downloaded interview from the On Being website. The interview was with ‘vocal magician and conductor’ Bobby McFerrin, and something he said early on in the interview really caught my attention.
We all like simple solutions. However much we may believe we are ‘above’ black-&-white dichotomies, that of course we understand that every situation is complex, nevertheless we have a brain that can only think of a very very few things at once. So it's unsurprising that we are drawn to solutions that can be summed up simply, that can fit comfortably within the limitations of working memory.