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Prevalence of Parkinson's Disease

After Alzheimer's disease, the second most common neurodegenerative disorder is Parkinson’s disease. In the U.S., at least 500,000 are believed to have Parkinson’s, and about 50,000 new cases are diagnosed every year1 (I have seen other estimates of 1 million and 1.5 million — and researchers saying the numbers are consistently over-estimated while others that they are consistently under-estimated!). In the U.K., the numbers are 120,000 and 10,0002.

Let's look a little deeper into the value of mnemonics for knowledge acquisition. By “knowledge acquisition”, I mean the sort of information you learn from textbooks — information that is not personal, that you need for the long-term.

In this context, I believe the chief value of mnemonic strategies is to help you recall information that needs to be remembered in a particular order. Thus we use mnemonics to help us remember the order of the planets, the order of musical notes on the stave, the order of the colors in a rainbow.

I’ve always been interested in the body’s clocks — and one of the most interesting things is that it is clocks, in the plural. It appears the main clock is located in a part of the brain structure called the hypothalamus (a very important structure in the brain, although not one of much importance to learning and memory). The part of the hypothalamus that regulates time is called the suprachiasmatic nuclei. These cells contain genes that switch on, off, and on again over a 24-hour period, and send electrical pulses and hormones through the body. This is the body’s master clock.

Children learn. It’s what they do. And they build themselves over the years from wide-eyed baby to a person that walks and talks and can maybe fix your computer, so it’s no wonder that we have this idea that learning comes so much more easily to them than it does to us. But is it true?

There are two particular areas where children are said to excel: learning language, and learning skills.

The other day I was sitting in the sunshine in my living room going through some journal articles I'd photocopied. I realized I needed to staple the pages together and went down to my study to get the stapler. Approaching my desk, I decided to check my email while I was there. And then, I decided to check my library account online to see whether a book I had requested had turned up. When I'd done that, I went back upstairs to my papers. Where I realized, of course, that I'd forgotten the stapler.

We don’t deliberately practice our memories of events — not as a rule, anyway. But we don’t need to — because just living our life is sufficient to bring about the practice. We remember happy, or unpleasant, events to ourselves, and we recount our memories to other people. Some will become familiar stories that we re-tell again and again. But facts, the sort of information we learn in formal settings such as school and university, these are not something we tend to repeatedly recount to ourselves or others — not for pleasure anyway!

What do we mean by word-finding problems?

Here are some examples:

  • increasing use of circumlocutions rather than specific terms (e.g., "I wonder where the thing that goes here is")
  • use of empty phrases, indefinite terms, and pronouns without antecedents (i.e., referring to something or someone as "it" or "him / her" without first identifying them by name)
  • increased frequency of pauses

These problems are all characteristic of Alzheimer's, but also, to a much lesser extent, of normal aging.

LBD: What is it?

Lewy Body Dementia is so called because the brains of affected people develop abnormal spherical masses of protein, called Lewy bodies, inside nerve cells. Lewy bodies are associated with Parkinson’s disease as well as dementia. Thus Lewy body dementia can refer to both Parkinson’s disease dementia and “dementia with Lewy bodies”. Lewy bodies are also often found in the brains of those with Alzheimer’s disease.

Unlike Alzheimer’s, however, dementia with Lewy bodies characteristically (but not invariably) begins with visual hallucinations.

In a 1987 experiment (1), readers were presented with a text that included one or other of these sentences:

or

Both texts went on to say:

This post is the fourth and last part in a four-part series on how education delivery is changing, and the set of literacies required in today’s world. Part 1 looked at textbooks; Part 2 at direct instruction/lecturing; Part 3 at computer learning.. This post looks at learning models and types of literacy.

 

Literacy. What does it mean?