Articles

LBD: What is it?

Lewy Body Dementia is so called because the brains of affected people develop abnormal spherical masses of protein, called Lewy bodies, inside nerve cells. Lewy bodies are associated with Parkinson’s disease as well as dementia. Thus Lewy body dementia can refer to both Parkinson’s disease dementia and “dementia with Lewy bodies”. Lewy bodies are also often found in the brains of those with Alzheimer’s disease.

Unlike Alzheimer’s, however, dementia with Lewy bodies characteristically (but not invariably) begins with visual hallucinations.

"Consolidation" is a term that is bandied about a lot in recent memory research. Here's my take on what it means.

Becoming a memory

Initially, information is thought to be encoded as patterns of neural activity — cells "talking" to each other. Later, the information is coded in more persistent molecular or structural formats (e.g., the formation of new synapses). It has been assumed that once this occurs, the memory is "fixed" — a permanent, unchanging, representation.

Until recent times, attention has always been quite a mysterious faculty. We’ve never doubted attention mattered, but it’s only in the past few years that we’ve appreciated how absolutely central it is for all aspects of cognition, from perception to memory. The rise in our awareness of its importance has come in the wake of, and in parallel with, our understanding of working memory, for the two work hand-in-hand.

Humans have a long tradition of holding genes responsible for individual differences in behavior (of course, we called it "blood", then, or "family"). In the 20th century, a counter-belief arose: that it was all down to environment, to upbringing. In more recent decades, we have become increasingly aware of how tightly and complexly genes and environment are entwined.

Distributed practice more effective than massed practice

It has long been known that spacing practice (reviewing learning or practicing a skill at spaced intervals) is far more effective than massed practice (in one heavy session). An interesting example of this comes from a study that aimed to find the best way of teaching postmen to type (this was at the request of the British Post Office). The researchers put postmen on one of four schedules:

Knowing a number of effective strategies for reading and note-taking, practicing and memorizing, is vital, but it's not the whole story. There is also a category of strategies we might term 'support' strategies. These include strategies aimed at setting goals, managing time and effort, and monitoring your performance and progress. In study, these come under the concept of self-regulation, which is related to the more general concept of metamemory.

Recently a “Framework for Success in Postsecondary Writing” came out in the U.S. This framework talked about the importance of inculcating certain “habits of mind” in students. One of these eight habits was metacognition, which they defined as the ability to reflect on one’s own thinking as well as on the individual and cultural processes used to structure knowledge.

Remembering a skill is entirely different from remembering other kinds of knowledge. It’s the difference between knowing how and knowing that.

The story method (sometimes called the sentence mnemonic) is the most easily learned list-mnemonic strategy, although it is not as widely known as the other simple methods we’ve talked about so far.

As its name suggests, the story method involves linking words to be learned in a story. While this is most obviously useful for learning actual lists, it can also be used for remembering the main points of a passage. In such a case, you need to reduce each point to a single word, which hopefully has the power to recall the whole point.

Alzheimer's disease currently affects one in 10 people over age 65 and nearly half of those over age 85.

More than 19 million Americans say they have a family member with the disease, and 37 million say they know somebody affected with Alzheimer's.

In the United States, the average lifetime cost per Alzheimer patient is US$174,000. (These figures are from the U.S. Alzheimer's Association).